Supernatural

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Back in the day, brothers Frank and Joe Hardy helped their dad out by collaring smugglers and thieves; Supernatural’s Sam and Dean Winchester take on slightly more daunting missions, like sending Lucifer back to hell and holding off the apocalypse. This bona fide CW hit began in 2005 as a monster-of-the-week show about urban myths like Bloody Mary, but matured over time into what creator Eric Kripke called “this massive, Byzantine mythology of angels and demons… and their destinies for the world.” That’s all very grand, but fundamentally Supernatural—led by charismatic stars Jared Padalecki and Jensen Ackles—has always been about family and personal connection—in Kripke’s words, “the only thing that gives life meaning.”